Adverse Effects of Organochlorine Pesticide Residues on Biochemical Parameters and Oxidative Stress in Libyan Agricultural Workers

Agricultural workers are in danger of being exposed to toxic substances such as pesticides. To estimate the individual handling pesticides, bio-monitoring effects on agricultural is required. There has been no research previously conducted among Libyan workers. This was designed study biochemical parameters impacts pesticide contamination at Aljebal Alakhtar, Libya. 45 blood samples were taken from male agriculture Alakhtar who had pesticides crop fields for a long time, while 25 group people not (control). Kits used assess plasma ALT, AST, ALP, GST, SOD, total protein, albumin, globulin, bilirubin, cholesterol, triglycerides, HDL-C, LDL-C, VLDL-C, urea, and creatinine. The thiobarbituric acid reactive (TBARS) assay evaluate lipid peroxidation serum. Using gas chromatography-electron capture detector, tested organochlorine residues (GC-ECD). In comparison controls, significantly higher ALT activities, well levels profile, creatinine, TBARS concentrations. Furthermore, long-term exposure also related reduceing reduced HDL-C levels. Pesticide seems influence various markers general. These biomarkers appear be indicative pesticide-related deleterious workers, indicating that they should routine monitoring impacts.